You can unlock Fusion Mode by first beating the game on Normal. Choosing that completed file and copy it to another slot, then select New Game. Select “amiibo” at the difficulty choice and scan the Metroid amiibo.
Metroid: Samus Returns Review:
https://www.youtube.com/watch?v=peDKQjR71q8
New Nintendo 3DS XL Samus Edition Unboxing:
https://www.youtube.com/watch?v=AakxVB_VQnE
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